The working area of this VL is all districts of Eastern Development Region (EDR). In this eastern region, there are three zones (Mechi, Koshi and Sagarmatha) and 16 districts. Recently 14 districts of EDR are placed in Province no.1 and 2 districts (Siraha and Saptari) are in Province no.2.Geographically, the region is divided into three eco-zones (high hills, mid hills and terai).

High hills:
This eco- zones lies in the northern part of the region covering Taplejung district of Mechi zone, Sankhuwasabha district of Koshi zone and Solukhumbu district of Sagarmatha zone. Livestock rearing is the main occupation of the farmers in this region. Yak/Nak, chauri, sheep and goat are being reared in this region.

Mid-hills:
This region falls between high hills on its north and terai at the south. Panchthar, Illam, Dhankuta, Terahthum, Bhojpur, Okhaladhunga, Khotang, and Udaypur districts are under this eco-zone. Farmers follow mixed farming system and agro-based livestock industries are their main occupation. Cattle, buffalo, swine, goat are being reared in this region. Poultry and rabbit farming are also popular among the farmers

Terai:
Jhapa, Morang, Sunsari, Saptari and Siraha districts of Nepal are under this eco-zone. Though traditional system of livestock rearing is followed in this region, in recent years, poultry, dairy industries,goat and piggery are being commercialized especially in east-west highway corridor.

To provide proper laboratory diagnosis and improve in the quality of veterinary services, the government has established five regional laboratories, one in each development region of the country. Primary laboratories in 55 and basic laboratories in 15 districts have been established to improve and upgrade existing disease diagnosis system. Out of 15, four basic laboratory buildings with some diagnostic facilities are being newly constructed in Jhapa, Illam , Dhankutta and Udaypur in F/Y 073/074.

After Federalism the Provincial Government of Province-1 has made only 8 Vetrinary Hospital and Livestock expert services center in Jhapa, Morang, Sunsari, Udaypur, Sankhuwasava, Panchthar, Dhankutta and Okhaldhunga. Remaining 6 districts namely Ilam, Taplejung, Terrahthum, Bhojpur, Khotang and Solu are designed as a contact Center of Jhapa, Panchthar, Dhankutta, Sankhuwasava, Udaypur and Okhaldhunga respectively.